Single molecule microarrays have been used in quantitative proteomics, in particular, single cell analysis requiring high sensitivity and ultra-low limits of detection. In this paper, several image ...

A carefully thought out method of harvesting and arraying tissue samples into blocks provides a simple but powerful way of reliably producing extremely large tissue microarrays using commonly ...

Microarrays provide a way of organizing biological samples for high-throughput analysis. Samples are arranged in columns and rows upon a support surface consisting of a glass slide, a nitrocellulose ...

Scientific advances in the field of genetics and gene-expression profiling have revolutionized the concept of patient-tailored treatment. Analysis of differential gene-expression patterns across ...

Interim Executive Director, Biodesign Institute Director, Biodesign Institute's Virginia G. Piper Center for Personalized Diagnostics; Virginia G. Piper Chair of Personalized Medicine; Pr ...

A protein microarray consists of the immobilization of proteins in organized rows and columns upon a support structure. The structure of the protein microarray allows for high-throughput analysis of ...

This Proven Technology Continues To Find Its Niche in the Modern Molecular Toolkit The advent of microarray technology has a much longer history than many realize. Ask any scientist “What is a ...

Curious about how to detect and characterize tumor-derived biomarkers from liquid biopsy samples? Genomics-based methods now provide access to more molecular data than ever before, delivering cancer ...

Twenty pneumococcal serotyping methods were put to the test. Medical doctors express concern about healthcare quality measures in the United States. Many recently developed pneumococcal serotyping ...

An international research team led by the University of Vienna has succeeded in developing a new version of RNA building blocks with higher chemical reactivity and photosensitivity. This can ...

Relationship of pro-angiogenic factor Cyr61to colorectal cancer development and prognosis. Background: Microarrays are widely used to study gene expression patterns in cancer. In colorectal cancer, it ...

Early Completion of Model-Assisted Designs for Dose-Finding Trials Accurate assessment of a molecular classifier that guides patient care is of paramount importance in precision oncology. Recent years ...